Why the study?
Reverse takotsubo cardiomyopathy is an uncommon variant characterized by basal hypokinesis with preserved apical contraction, and atypical cases triggered by acute respiratory failure rather than abrupt emotional stressors are rarely reported.
Population
A 69-year-old woman with CAD, COPD, and acute respiratory failure
Design
Case report
Key result
A 69-year-old woman developed reverse takotsubo cardiomyopathy triggered by acute respiratory failure and chronic grief, with her ejection fraction recovering from 40% to 60% after 4 months of supportive care.
Authors
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Respiratory failure may trigger reverse takotsubo; this case extends known precipitants but remains hypothesis-generating.
Case Report (n=1)
No
Reverse Takotsubo cardiomyopathy should be considered in patients with ACS-like presentations during acute critical illness, even when emotional stressors are chronic.
Cwalina et al. (2026) conducted a case report in Reverse takotsubo cardiomyopathy (n=1). Acute respiratory failure and chronic grief was evaluated on Left ventricular ejection fraction recovery. A 69-year-old woman developed reverse takotsubo cardiomyopathy triggered by acute respiratory failure and chronic grief, with her ejection fraction recovering from 40% to 60% after 4 months of supportive care.