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July 8, 2026Small

Composite Hydrogel With Ultra‐High Mechanical Anisotropy and Biotissue‐Like Softness by Confining Electrostatic and Entropic Repulsion Between Cofacially Aligned Nanosheets

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Authors

YZYunlei ZhangKYKuniyo YamadaTKTakayuki Kikuchi

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Overview

Randomized trial demonstrates mechanical anisotropy and softness in hydrogels, suggesting novel biomedical applications.

Key Points

  • This study aims to develop a hydrogel that combines high mechanical anisotropy with low elastic modulus for biomedical use.
  • Hydrogel developed using magnetically oriented, negatively charged nanosheets.
  • Nanosheet concentration optimized to enhance anisotropy without losing alignment.
  • Polymer network adjusted for less crosslinking to facilitate water expulsion and densification.
  • Hydrogel achieves an anisotropy factor of 380 (E hard / E soft) with soft modulus of 3.1 kPa.
  • Increased nanosheet concentration effectively enhances anisotropy until viscosity limits alignment.
  • Hydrogel shows improved vibration insulation and rectification properties.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a4de93fd2ea289ef6283808https://doi.org/10.1002/smll.74363
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Also Consider

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