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July 8, 2026Urogynecology

Rate of IPG Placement for Sacral Neuromodulation in Patients With CNS Pathology

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Authors

KPKunal PatelEKElectra KornMFMichael Flynn

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Overview

Retrospective study assesses IPG implantation rates for SNM in women with CNS pathology and overactive bladder, indicating variability based on diagnosis.

Key Points

  • This study aims to evaluate the rate of internal pulse generator implantation for sacral neuromodulation in women with CNS-related urinary issues.
  • Retrospective analysis utilizing TriNetX Research Network data from 2010 to 2025.
  • Cohorts were defined by CNS pathology including dementia, Parkinson's disease, stroke, and multiple sclerosis among women with overactive bladder and urinary retention.
  • Primary outcome measured was the rate of neurostimulator device IPG placement within specified timeframes.
  • Significantly lower SNM IPG implantation rates were observed in dementia patients (47.73%) compared to controls (55.56%).
  • No significant differences in implantation rates for Parkinson's disease, stroke, MS, and NPH cohorts were found.
  • In urinary retention cohorts, SNM IPG rates were statistically similar when compared to the control population.

Cite This Study

Patel et al. (2026) studied this question.

synapsesocial.com/papers/6a4de9add2ea289ef6283b2dhttps://doi.org/10.1097/spv.0000000000001863
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sacral Neuromodulation Outcomes for Managing Urinary Incontinence in Patients With Overactive and Neurogenic Bladder2026
  2. 2Sacral Neuromodulation in Non‐Neurogenic Lower Urinary Tract Symptoms: Clinical Efficacy and Safety2026
  3. 3Patients’ Perspectives and Challenges with Sacral Neuromodulation Implantable Pulse Generator2026
  4. 4Sacral Neuromodulator Surgery: Is There an Ideal Candidate?2025
  5. 5Outcomes following intradetrusor onabotulinumtoxinA injections and sacral neuromodulation in older men2026