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July 8, 2026Bioresources and BioprocessingOpen Access

Solvent-driven modulation of phenolic composition and biofunctional activities of three Mentha aquatica formulations: integrated in vitro and in silico insights

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Authors

MTMeryem TourabiAMAmira MetouekelMJMohamed Jeddi

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Overview

Randomized trial examines phenolic composition and bioactivity in Mentha aquatica extracts, suggesting solvent choice impacts benefits.

Key Points

  • This research aims to assess how different solvents affect the phenolic composition and bioactivity of Mentha aquatica extracts.
  • Characterization of extracts using HPLC-ESI-FULL-MS.
  • Evaluation of total phenolic and flavonoid contents with Folin-Ciocalteu and aluminum trichloride methods.
  • Assessment of antibacterial capacity via microdilution technique to determine MIC and MBC.
  • Hydroethanolic extract had the highest total phenolic content (62.2 ± 1.2 mg GAE/g DW) and flavonoid content (29.15 ± 0.09 mg QE/g DW).
  • The antioxidant capacity recorded IC50 of 0.060 ± 0.001 mg/mL in the DPPH assay.
  • Antibacterial potential ranged from 0.78 ± 0.05 mg/mL to 12.6 mg/mL.

Cite This Study

Tourabi et al. (2026) studied this question.

synapsesocial.com/papers/6a4dea28d2ea289ef6283f51https://doi.org/10.1186/s40643-026-01093-6
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Also Consider

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  1. 1Solvent Polarity Effects on Phenolic Fingerprint and Biological Activities, Using Three Different Extractions Formulation for Examining of <em>Mentha aquatica</em> Leaf Extracts: An In Vitro and In‐Silico Investigation2024
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  4. 4Analysis of phenolic contents and biological activities of wild mint, Mentha longifolia (L.) L.2024 · 6 citations
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