Recent Advances on Mechanochemical Conversion of Per/Polyfluoroalkyl Substances

Per‐ and polyfluoroalkyl substances (PFAS) represent a class of important artificial chemicals with high thermal stability and water/oil repellency, making them widely used across various sectors of human activity. The strong carbonfluorine bonds impart exceptional chemical resistance, which has led to PFAS being known as “forever chemicals” due to their low biodegradability and long environmental persistence. Additionally, PFAS exhibit significant intergenerational bioaccumulative toxicity, prompting China to list them as typical emerging pollutants in the Priority List of Contaminants of Concern for Control . To address the increasingly severe PFAS pollution crisis, the scientific and industrial communities have developed diverse technical approaches, including landfilling, incineration, chemical degradation, and photocatalytic conversion. Notably, mechanochemistry has emerged as an innovative technology with promising application prospects for PFAS degradation in recent years. Based on the classification of ball‐milling modes and the properties of comilling reagents, this article reviews recent advances in the mechanochemical degradation of PFAS, with emphasis on reaction mechanisms and fluorine resource upcycling. Current challenges and future outlook for the development of safer and greener mechanochemical conversion of PFAS are also discussed.