Key result
Preoperative total atrial conduction time derived on tissue Doppler imaging (PA-TDI duration) was an independent predictor of postoperative atrial fibrillation following off-pump coronary artery bypass grafting (OR 1.11, 95% CI 1.06-1.16, P=0.0001).
Why the study?
Does preoperative PA-TDI duration predict postoperative atrial fibrillation in patients undergoing isolated OPCAB?
Observational (n=88)
No
Does preoperative PA-TDI duration predict postoperative atrial fibrillation in patients undergoing isolated OPCAB?
Odds Ratio: 1.11 (95% CI 1.06–1.16)
p-value: p=0.0001
Preoperative PA-TDI duration measured by tissue Doppler imaging is a strong independent predictor of postoperative atrial fibrillation after off-pump CABG.
May inform preoperative risk stratification in off-pump CABG; hypothesis-generating and requires prospective validation before practice change.
BACKGROUND: Postoperative atrial fibrillation (POAF) is a common complication of cardiac surgery and results in increased health-care utilization. This study identified new transthoracic echocardiographic predictors of POAF using an index of the total atrial conduction time derived on tissue Doppler imaging (PA-TDI duration) in patients undergoing off-pump coronary artery bypass grafting (OPCAB). METHODS AND RESULTS: A total of 88 patients undergoing isolated OPCAB were enrolled. They were examined preoperatively on transthoracic echocardiography with tissue Doppler evaluations and monitored postoperatively with continuous electrocardiographic telemetry for 7 days. POAF occurred in 35 patients (39.8%). Patients with POAF had a significantly longer duration of hospital stay than those without (44.9±6.2 vs. 37.3±3.3 days, P=0.04). Multivariate analysis showed that PA-TDI duration (odds ratio [OR], 1.11; 95% confidence interval [CI]: 1.06-1.16; P=0.0001) and left atrial volume index (LAVI; OR, 1.11; 95% CI: 1.02-1.20; P=0.01) were independent predictors of POAF. Moreover, PA-TDI duration was more reliable, given an area under the receiver operating characteristic curve of 0.85 (sensitivity, 74.3%; specificity, 86.8%). CONCLUSIONS: PA-TDI duration was an independent predictor of POAF following OPCAB. Awareness of risk of POAF may lead to the prevention of POAF, a rapid response to POAF, shortened hospital stay, and improved prognosis.
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Fujiwara et al. (2013) conducted an observational in Postoperative atrial fibrillation after off-pump coronary artery bypass grafting (n=88). Preoperative PA-TDI duration (total atrial conduction time) vs. Shorter PA-TDI duration was evaluated on Postoperative atrial fibrillation (POAF) (OR 1.11, 95% CI 1.06-1.16, p=0.0001). Preoperative total atrial conduction time derived on tissue Doppler imaging (PA-TDI duration) was an independent predictor of postoperative atrial fibrillation following off-pump coronary artery bypass grafting (OR 1.11, 95% CI 1.06-1.16, P=0.0001).
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