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May inform arrhythmic risk stratification in DCM; hypothesis-generating and requires prospective validation.
DCM, dilated cardiomyopathy; HF, heart failure; HR, multivariate hazard ratio associated with each genotype (with the genotype-negative group serving as reference); ICD, implantable cardioverter defibrillator; LP/P variants, likely pathogenic or pathogenic variants; NICM, non-ischaemic cardiomyopathy; NS, non-significant; TTN, titin. *High arrhythmic-risk genes: LMNA, desmosomal genes, RMB20, FLNC, TMEM43, and PLN. **Other DCM-causing genes: BAG3, MYH7, TNNT2, DMD, TPM1, JPH2, TNNI3, TBX20, EMD, ACTC1, PRDM16, SGCD, FKRP, NKX2-5, FKTN, and TNNC1.
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Waroux et al. (2025) studied Dilated cardiomyopathy.
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