Key result
Diastolic dysfunction in fetal cardiomyopathy was associated with an 8-fold increased risk of perinatal mortality relative to other echocardiographic parameters.
Observational (n=55)
Odds Ratio: 8
Fetal cardiomyopathy carries a high perinatal mortality rate (63%), with diastolic dysfunction being the strongest predictor of death.
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Diastolic dysfunction may aid perinatal risk stratification in fetal cardiomyopathy; leaves open whether it informs management or trials.
Pedra et al. (2002) conducted an observational in Fetal cardiomyopathy (n=55). Diastolic dysfunction vs. Other echocardiographic parameters was evaluated on Perinatal mortality (8-fold increased risk). Diastolic dysfunction in fetal cardiomyopathy was associated with an 8-fold increased risk of perinatal mortality relative to other echocardiographic parameters.
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