Key result
Treatment with high-dose dexamethasone and plasmapheresis decreased maternal SS-B (La) antibodies and ameliorated fetal cardiac disease, although complete heart block persisted.
Why the study?
Does maternal treatment with high-dose dexamethasone and plasmapheresis improve fetal myocarditis and heart block due to systemic lupus erythematosus?
Population
1 pregnant woman with systemic lupus erythematosus whose fetus developed pericarditis, myocarditis, and…
Design
Case_report
Follow-up
Until delivery at week 31
Authors
Loading...
May support targeted therapy in fetal lupus; leaves open whether it prevents progression to irreversible block.
Case Report (n=1)
Does maternal treatment with high-dose dexamethasone and plasmapheresis improve fetal myocarditis and heart block due to systemic lupus erythematosus?
Maternal treatment with high-dose dexamethasone and plasmapheresis may ameliorate fetal carditis associated with systemic lupus erythematosus, though complete heart block may persist.
Buyon et al. (1987) conducted a case report in Fetal myocarditis with acquired heart block due to systemic lupus erythematosus (n=1). High-dose dexamethasone and plasmapheresis was evaluated on Amelioration of cardiac disease and decrease in maternal SS-B (La) antibodies. Treatment with high-dose dexamethasone and plasmapheresis decreased maternal SS-B (La) antibodies and ameliorated fetal cardiac disease, although complete heart block persisted.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: