Key result
Hyperbaric oxygen therapy and prompt positioning achieve full neurological recovery in biopsy-induced cerebral gas embolism.
Why the study?
Cerebral arterial gas embolism is a rare complication of percutaneous CT-guided lung biopsy that can lead to a very poor prognosis without prompt recognition and urgent treatment.
Case Report (n=1)
No
Prompt recognition and treatment with hyperbaric oxygen therapy can lead to full neurological recovery in patients with cerebral arterial gas embolism complicating lung biopsy.
May support hyperbaric oxygen for cerebral gas embolism after lung biopsy; hypothesis-generating and requires prospective validation before practice change.
Cerebral arterial gas embolism is a rare complication of percutaneous CT-guided lung biopsy i.e. associated with seizures and neurological deficits such as stroke. Failure to promptly recognise and urgently treat can lead to a very poor prognosis. This case describes an 80-year-old woman undergoing a CT-guided lung biopsy for histological assessment of a suspected malignant cavitating lung lesion. Shortly after the procedure, the patient developed complete left-sided hemiparesis. A CT scan of the head demonstrated air in the right middle cerebral artery territory. Urgent transfer to a specialist centre for gold standard hyperbaric oxygen therapy was critical to optimise patient recovery. To prevent further air migration, the patient was placed in the Trendelenburg and left lateral decubitus position and high flow oxygen was administered, while awaiting transfer. Following hyperbaric oxygen therapy, the patient was stepped down to a stroke unit for rehabilitation. Full neurological recovery was made. This case highlights that radiologists should be well-versed in recognising the signs and immediate management of air embolism and anticipate it as a rare but severe complication of lung biopsy.
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Ramdhun et al. (2026) conducted a case report in Cerebral arterial gas embolism (CAGE) (n=1). Hyperbaric oxygen therapy (HBOT) was evaluated on Neurological recovery. Hyperbaric oxygen therapy and prompt positioning resulted in full neurological recovery in a patient with cerebral arterial gas embolism complicating a CT-guided lung biopsy.
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