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July 9, 2026Journal of Addictive Diseases

Evidence-informed approaches to medication management for opioid use disorder in special populations: a narrative review

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Authors

ZAZahraa AtouiEmory UniversityAFAdam FakhriEmory UniversityAMAniket MalhotraUniversity of Alabama at Birmingham

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Implication

Narrative review summarizes evidence on medication management for opioid use disorder in special populations, indicating tailored strategies are necessary.

Key Points

  • This review aims to summarize evidence-based approaches for medication management of opioid use disorder (OUD) specifically addressing the needs of special populations.
  • Narrative review of evidence and guidelines regarding medication management for OUD in special populations.
  • Population-focused considerations included individuals with hepatic, renal, cardiovascular disease, HIV/AIDS, pregnancy, and adolescents.
  • Analysis of safety profiles, treatment retention rates, and barriers to medication utilization.
  • Methadone is linked to the highest treatment retention but requires careful monitoring for patients with comorbidities.
  • Buprenorphine shows a favorable safety profile with fewer drug interactions across medically complex populations.
  • Access gaps persist, particularly among adolescents, highlighting the need for targeted implementation strategies.

Cite This Study

Atoui et al. (2026) studied this question.

synapsesocial.com/papers/6a4f3a702b81a944af574ca2https://doi.org/10.1080/10550887.2026.2695127
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