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This research investigates the prevalence and interaction of feline and canine coronaviruses in specific regions of China.

July 9, 2026Veterinary SciencesOpen Access

Cross-Species Transmission and Recombination Between Feline and Canine Coronaviruses in Jiangsu–Zhejiang Region in 2025

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This research investigates the prevalence and interaction of feline and canine coronaviruses in specific regions of China.
Established a universal RT-qPCR assay for FCoVs and CCoVs.
Analyzed 700 clinical samples, including 501 from cats and 199 from dogs, for viral detection.
Conducted phylogenetic analysis and recombination analyses on identified virus sequences.
Detected a total of 92 positive samples (13.14%, 92/700), with 79 from cats (15.76%, 79/501) and 13 from dogs (6.5%, 13/199).
Identified inter-species recombination events and one CCoV-I sequence from a feline sample and one FCoV-II sequence from a canine sample.
Revealed cross-species transmission and recombination occurrences between FCoV and CCoV among companion animals in Jiangsu–Zhejiang.

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Randomized trial evaluates cross-species transmission of coronaviruses in companion animals, suggesting significant outbreak implications.

Lin et al. (2026) studied this question.

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Randomized trial evaluates cross-species transmission of coronaviruses in companion animals, suggesting significant outbreak implications.