BACKGROUND: No vaccines are currently licensed for the prevention of METHODS: In this multicenter, double-blind, randomized, placebo-controlled trial, we assigned, in a 1:1 ratio, men who have sex with men (MSM) to receive two doses of 4CMenB or placebo. All the participants had recently received a diagnosis of RESULTS: From July 2021 through May 2023, a total of 654 participants underwent randomization, of whom 587 were included in the primary analysis. The incidence of CONCLUSIONS: 4CMenB did not result in a lower incidence of
Seib et al. (Wed,) studied this question.