Key result
Concurrent PE and obesity linked to higher mortality, especially in women, middle-aged, and Black adults.
Why the study?
Obesity increases the risk of pulmonary embolism through multiple mechanisms, prompting an examination of mortality trends in patients with coexisting PE and obesity.
Observational
Yes
Mortality from concurrent pulmonary embolism and obesity in the US has risen significantly from 1999 to 2020, with accelerating rates since 2018 and disproportionate burdens falling on middle-aged adults, women, non-Hispanic Black individuals, and nonmetropolitan residents.
Alerts clinicians to rising PE-obesity mortality in specific groups; leaves open whether targeted strategies improve survival.
Background: Obesity increases the risk of pulmonary embolism (PE) through multiple mechanisms. Objectives: This study examined mortality trends in patients with coexisting PE and obesity. Methods: < .05. Conclusions: The analysis reveals a significant rise in mortality from concurrent PE and obesity, with higher rates observed in women, middle-aged adults, non-Hispanic Black individuals, and residents of nonmetropolitan areas. These findings highlight the need for targeted interventions in these high-risk groups.
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Goyal et al. (2025) conducted an observational in Pulmonary embolism and obesity. Obesity vs. Without obesity was evaluated on Mortality (p=<.001). Concurrent pulmonary embolism and obesity was associated with a significant rise in mortality (P<0.001), with higher rates in women, middle-aged adults, and non-Hispanic Black individuals.
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