Key result
Surgical excision of a calcified amorphous tumor and mitral valve replacement successfully treated a 38-year-old woman with acute cerebral infarction, with no further embolic events over 10 months.
Case Report (n=1)
This case report suggests that calcium build-up along the mitral annulus and fibrotic tissue rupture may contribute to the initiation and progression of cardiac calcified amorphous tumors leading to cerebral infarction.
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Calcified amorphous tumors merit inclusion in embolic stroke differentials; extends sparse case data but remains hypothesis-generating.
We report the case of a 38-year-old woman who was admitted for acute cerebral infarction linked to a cardiac calcified amorphous tumor (CAT) and related mitral annular calcification (MAC). The cardiac mass was removed, and mitral valve replacement surgery was performed. Pathological examination revealed an amorphous accumulation of degenerating material within both lesions, indicating that build-up of calcium along the mitral annulus and subsequent rupture of the fibrotic tissue may be involved in the initiation and progression of CAT.
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Aizawa et al. (2018) conducted a case report in Acute cerebral infarction and cardiac calcified amorphous tumor (n=1). Surgical excision and mitral valve replacement was evaluated on Clinical recovery and prevention of further embolic events. Surgical excision of a calcified amorphous tumor and mitral valve replacement successfully treated a 38-year-old woman with acute cerebral infarction, with no further embolic events over 10 months.
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