Key result
Although biomarker concentration distributions may differ between men and women with acute coronary syndromes and heart failure, the clinical implications of these differences remain unclear.
Why the study?
Should biomarkers in ACS and heart failure be interpreted differently for men and women?
Should biomarkers in ACS and heart failure be interpreted differently for men and women?
This review highlights that while biomarker concentrations differ by sex in ACS and HF, further research is needed to determine if sex-specific reference limits improve clinical care.
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Should not yet guide sex-specific biomarker thresholds in ACS or HF; leaves open need for outcome-focused sex-stratified studies.
Motiwala et al. (2013) conducted a review in Acute coronary syndromes (ACS) and heart failure (HF). Biomarkers vs. Men vs women was evaluated. Although biomarker concentration distributions may differ between men and women with acute coronary syndromes and heart failure, the clinical implications of these differences remain unclear.
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