Key result
Infections of novel cardiac implantable devices are uncommon but potentially fatal complications that present with non-specific signs like fever and often require surgical removal and systemic antibiotic therapy.
Why the study?
Although novel cardiac devices have mechanisms conferring infection resistance, uncommon device-associated infections in high-risk comorbid patients can lead to serious complications and increased mortality.
What is the incidence, clinical presentation, management, and prognosis of infections associated with novel cardiac implantable devices?
What is the incidence, clinical presentation, management, and prognosis of infections associated with novel cardiac implantable devices?
This review highlights that while novel cardiac devices have features that reduce infection risk, infections that do occur carry high morbidity and mortality due to patient comorbidities.
Infection-resistant novel devices may aid high-risk patients; leaves open randomized outcome trials.
Novel cardiac devices, including the MitraClip system, occluder devices, leadless pacemakers, and subcutaneous implantable cardioverter defibrillators (S-ICD), are mostly used in the management of patients who are at high risk for surgery and/or developing infections. Several mechanisms render most of these devices resistant to infection, including avoiding long transvenous access and novel manufacturing material. Since subjects who use these devices already endure several comorbid conditions, uncommon cases of device-associated infection could result in serious complications and increased mortality. In this review, we aim to summarize the current state of evidence on the incidence, clinical presentation, management, and prognosis of new cardiac devices' associated infection.
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Ramadan et al. (2022) conducted a review in Infection of novel cardiac implantable devices. Novel cardiac implantable devices was evaluated. Infections of novel cardiac implantable devices are uncommon but potentially fatal complications that present with non-specific signs like fever and often require surgical removal and systemic antibiotic therapy.
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