Key result
Bicycle training for 5 weeks improved work capacity (p<0.02) and VO2/kg/min (p<0.0006) in post-MI patients with mildly depressed cardiac function, but not in those with very depressed function.
Why the study?
Does 5 weeks of bicycle training improve cardiopulmonary and hemodynamic parameters in post-myocardial infarction patients with left ventricular dysfunction and prior cardiac failure?
Does 5 weeks of bicycle training improve cardiopulmonary and hemodynamic parameters in post-myocardial infarction patients with left ventricular dysfunction and prior cardiac failure?
p-value: p=<0.02
Physical rehabilitation improves exercise tolerance in post-MI heart failure patients with mildly depressed cardiac function, but not in those with severely depressed function.
Exercise training may improve capacity only in milder post-MI LV dysfunction; hypothesis-generating, requires randomized confirmation before practice change.
The effects of bicycle training for 5 weeks were evaluated in 12 patients after myocardial infarction with left ventricular dysfunction (left ventricular ejection fraction < 40%) and at least one episode of cardiac failure in the past. The patients were divided into two groups of six according to the Weber classification: Group B (VO2/kg/min: 16-20) and Group C (VO2/kg/min: 10-15). Cardiopulmonary and hemodynamic parameters were evaluated during a maximal exercise test and a simultaneous catheterization of the right side of the heart before and after the training. An increase in the capacity for work was recorded in Group B (p < 0.02), while Group C remained unchanged. A statistically significant increase in minute ventilation (p < 0.05) and VO2/kg/min (p < 0.0006) was recorded in Group B. Group C showed an increase in the mean pulmonary arterial pressure (p < 0.03). All of the other parameters remained unchanged after training. We conclude that physical rehabilitation improves the tolerance to exercise in patients with a mildly depressed cardiac function (Group B) but not in patients with a very depressed cardiac function (Group C).
No takes yet. Share an insight, caveat, or question.
Scalvini et al. (2008) studied Myocardial infarction with left ventricular dysfunction and past cardiac failure (n=12). Bicycle training vs. Pre-training baseline was evaluated on Capacity for work (p=<0.02). Bicycle training for 5 weeks improved work capacity (p<0.02) and VO2/kg/min (p<0.0006) in post-MI patients with mildly depressed cardiac function, but not in those with very depressed function.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: