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September 18, 2023European Journal of Preventive CardiologyOpen Access

Cumulative social disadvantage and cardiovascular disease burden and mortality

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Why the study?

The study was designed to investigate the association between cumulative social disadvantage and cardiovascular disease burden and mortality in the general population.

Does low socioeconomic status increase the risk of cardiovascular disease and mortality in the general population?

Population

15 010 individuals aged 35 to 74 years from the Gutenberg Health Study

Comparison

Low socioeconomic status vs high socioeconomic status

Design

Cross-sectional and longitudinal cohort study

Follow-up

5- and 10-year follow-ups

Key result

Low socioeconomic status was associated with a 68% higher risk of incident cardiovascular disease at 10 years (OR 1.68; 95% CI 1.12-2.47) and an 86% higher risk of all-cause mortality.

Authors

OHOmar HahadDGDonya GilanJCJulian Chalabi

Discussion

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Overview

Social disadvantage links to higher CVD burden despite universal care; leaves open causal pathways for prospective trials.

Study Design

Type

Cohort (n=15,010)

Structured PICO

Does low socioeconomic status increase the risk of cardiovascular disease and mortality in the general population?

P
Population
15,010 individuals aged 35 to 74 years from the general population, followed for up to 10 years to investigate the association between socioeconomic status and cardiovascular disease.
E
Exposure
Low socioeconomic status (SES, measured via a validated questionnaire including education, occupation, and household net-income scores)
C
Comparator
High socioeconomic status (defined by validated cut-offs)
O
Outcome
Cardiovascular disease (composite of atrial fibrillation, coronary artery disease, myocardial infarction, stroke, chronic heart failure, peripheral artery disease, and/or venous thromboembolism) risk and mortality (cardiovascular and all-cause)composite

Main Result

Odds Ratio: 1.68 (95% CI 1.12–2.47)

Cumulative social disadvantage, specifically lower education and occupation levels, is associated with significantly higher risks of incident cardiovascular disease and mortality despite universal healthcare access.

Cite This Study

Hahad et al. (2023) conducted a cohort in Cardiovascular disease (n=15,010). Low socioeconomic status vs. High socioeconomic status was evaluated on Incident cardiovascular disease at 10-year follow-up (OR 1.68, 95% CI 1.12-2.47). Low socioeconomic status was associated with a 68% higher risk of incident cardiovascular disease at 10 years (OR 1.68; 95% CI 1.12-2.47) and an 86% higher risk of all-cause mortality.

synapsesocial.com/papers/6a50390e73bacd73dc784420https://doi.org/10.1093/eurjpc/zwad264
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