Key result
ASA physical status, tumor location, and disease stage significantly affected survival rates after rectal cancer surgery (P < 0.05), whereas patient gender did not (P > 0.05).
Why the study?
There were limited data describing different factors that influence survival rate of patients with rectal cancer.
Do gender, ASA physical status, tumor location, and disease stage influence survival rates in patients with rectal cancer after surgery?
Cohort (n=385)
No
Do gender, ASA physical status, tumor location, and disease stage influence survival rates in patients with rectal cancer after surgery?
p-value: p=<0.05
ASA physical status, tumor location, and disease stage, but not gender, significantly impact survival rates in patients following surgery for rectal adenocarcinoma.
ASA status, tumor location, and stage inform rectal cancer prognosis after excision, unlike gender; leaves open their utility for treatment decisions.
BACKGROUND: There are limited data describing different factors that influence survival rate of patients with rectal cancer. AIMS: Our aim was to determine the influence of patient gender, American Society of Anesthesiologists (ASA) physical status, the location of the tumor and stage of the disease on the patient survival rates after excision of rectal cancer. SETTINGS AND DESIGN: We included 385 patients who were operated between 2004 and 2014 in the University Clinical Center Maribor. The patients were treated due to rectal adenocarcinoma. We assessed survival rates according to gender, ASA physical status, the location of the tumor and stage of the disease with different statistical methods. SUBJECTS AND METHODS: To find the extent of correlation between factors and survival rate, we used means and medians, Log Rank test, Breslow test and Tarone-Ware test. RESULTS: According to patient gender, survival rate did not differ significantly (P > 0.05), however ASA physical status (P < 0.05), location of the tumor (P < 0.05) and stage of the disease (P < 0.05) significantly affected the survival rates. CONCLUSIONS: Our study showed that gender does not have a significant impact on survival rate as oposed to ASA physical status, the location of the tumor and stage of the disease.
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Nuhi Arslani (2020) conducted a cohort in Rectal adenocarcinoma (n=385). Patient gender, ASA physical status, tumor location, and disease stage was evaluated on Survival rate (p=<0.05). ASA physical status, tumor location, and disease stage significantly affected survival rates after rectal cancer surgery (P < 0.05), whereas patient gender did not (P > 0.05).
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