ESHRE position paper: international limits on the number of offspring per gamete donor

July 8, 2026Human ReproductionOpen Access

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Key Points

The aim is to establish international regulations on the number of offspring per gamete donor to protect donor-conceived individuals.
Developed by a multidisciplinary expert working group within ESHRE.
Incorporated feedback from 45 stakeholders, including donors, families, and fertility professionals.
Proposed a phased introduction of limits starting from 50 families to a maximum of 15 families per donor.
Recommends an EU-wide limit on families per gamete donor starting at 50 and reducing to 15 or lower.
Suggests a 20-year maximum distribution cap for donor gametes to new families after the first donation.
Proposes a monitoring system through EU-wide or national donor registries to ensure compliance.

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Position paper proposes EU-wide limits on donor offspring in families, indicating a need for standardized regulations.

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Frith et al. (2026) studied this question.

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