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July 10, 2026CureusOpen Access

Under the Surface: A Case of Secondary Delusional Infestation With Mood-Congruent Psychotic Features in a 56-Year-Old Woman

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Authors

ACAngela ChenTBTravis Brauer

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Overview

Case explores treatment of delusional infestation in a woman with bipolar disorder, suggesting implications for management strategies.

Key Points

  • This case aims to explore the relationship between delusional infestation and bipolar disorder exacerbated by stimulant use.
  • Detailed clinical assessment of a 56-year-old woman with a history of HIV and bipolar disorder.
  • Management involved divalproex sodium for mood stabilization and olanzapine for psychotic symptoms.
  • Utilized a communication strategy of empathetic neutrality to establish therapeutic rapport.
  • The patient showed significant reduction in distress and improved functionality by discharge.
  • Persistent delusional conviction remained, indicating partial response to treatment.
  • Highlights the role of dopaminergic pathways in delusional infestation pathophysiology.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a508bde6eeac72a437a04c9https://doi.org/10.7759/cureus.112268
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ekbom Syndrome in the context of psychotic depression and cocaine use: A case report2025
  2. 2Delusional parasitosis secondary to vascular pathology in an oncological patient: case study2025
  3. 3Delusional parasitosis: the importance of a multidisciplinary approach2024
  4. 4A Case of Delusional Parasitosis Secondary to Severe Iron Deficiency Anaemia in a Tertiary Care Hospital: An Area for Clinical Vigilance2024
  5. 5A Cohort-Based Study of Patients With Delusional Infestation: Characterizing the Patient Population2026