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July 10, 2026Asian Journal of Neurosurgery

Comparison of Microcuffed versus Uncuffed Endotracheal Tubes on Efficacy of Ventilation and Airway Complications in Pediatric Patients Undergoing Elective Neurosurgical Procedures in the Prone Position: A Randomized Controlled Trial

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Authors

SCSagar Satish ChavanRRRajasekar RamaduraiAKAswini Kuberan

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Overview

Randomized trial compares ventilation outcomes in pediatric patients with microcuffed and uncuffed tubes, indicating improved airway stability.

Key Points

  • This trial aims to compare the effectiveness of microcuffed and uncuffed endotracheal tubes regarding ventilation and airway complications in young children during neurosurgery.
  • Randomized controlled trial involving children under 8 years undergoing elective neurosurgery in the prone position.
  • Primary outcome was peritubal leakage measured via tidal volumes; secondary outcomes included tube exchange rates, intubation characteristics, and complications.
  • Statistical analyses were conducted using independent sample t-tests for continuous variables and chi-square tests for categorical variables.
  • Microcuffed tubes showed significantly lower peritubal leakage, with mean differences of -0.33 mL/kg in the supine position (95% CI -0.63 to -0.03; p=0.02) and -0.51 mL/kg in the prone position (95% CI -0.83 to -0.19; p=0.003).
  • Less frequent tube exchanges in the microcuff group (9.4% vs. 37.5%).
  • First-attempt intubation success was higher in the microcuffed group, with low airway complication rates in both groups.

Cite This Study

Chavan et al. (2026) studied this question.

synapsesocial.com/papers/6a508cc46eeac72a437a098fhttps://doi.org/10.1055/s-0046-1824757
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1To assess the ease of intubation and post-extubation complications of the airway due to the use of microcuffed endotracheal tubes and uncuffed endotracheal tubes2024 · 1 citations
  2. 2Cuffed versus uncuffed endotracheal tubes in neonates undergoing noncardiac surgeries: A randomized controlled trial2024 · 2 citations
  3. 3COMPARATIVE STUDY OF CLINICAL EFFECT OF CUFFED VS UNCUFFED ENDOTRACHEAL TUBE IN NEONATES UNDERGOING SURGERY UNDER GENERAL ANAESTHESIA2018
  4. 4Microcuff® Tubes in Neonates: Do we know the Safe cuff Pressures?2024
  5. 5Cuffed Endotracheal Tubes in Neonates2026