What question did this study set out to answer?

This study aims to compare 3-year oncologic outcomes between transanal total mesorectal excision and laparoscopic total mesorectal excision in mid and low rectal cancer.

July 10, 2026Surgical EndoscopyOpen Access

Outcomes of transanal vs laparoscopic total mesorectal excision for mid and low rectal cancer under routine clinical practice conditions

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Authors

CSChen SuThe Affiliated Yongchuan Hospital of Chongqing Medical University JDJunfeng DuChinese PLA General Hospital YXYang XieChongqing University

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Implication

Retrospective cohort study compares oncologic outcomes in patients with rectal cancer, suggesting similar effectiveness of surgical approaches.

Key Points

This study aims to compare 3-year oncologic outcomes between transanal total mesorectal excision and laparoscopic total mesorectal excision in mid and low rectal cancer.
Retrospective cohort study at a tertiary academic hospital from January 2018 to May 2022.
256 patients with mid and low rectal adenocarcinoma treated with total mesorectal excision were analyzed and propensity score matching yielded a cohort of 170 patients.
The median follow-up duration was 48 months.
At 3 years, local recurrence rates were 3.7% for TaTME and 4.8% for LapTME.
Distant metastasis rates were 13.0% for TaTME and 14.5% for LapTME.
Three-year disease-free survival rates were 83.3% for TaTME and 82.3% for LapTME, while overall survival was 88.9% for TaTME and 90.3% for LapTME.

Cite This Study

Su et al. (2026) studied this question.

synapsesocial.com/papers/6a508d096eeac72a437a0c75 https://doi.org/10.1007/s00464-026-13057-0

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Implication

Retrospective cohort study compares oncologic outcomes in patients with rectal cancer, suggesting similar effectiveness of surgical approaches.

Outcomes of transanal vs laparoscopic total mesorectal excision for mid and low rectal cancer under routine clinical practice conditions

Discussion

Member takes

Implication

Key Points

Cite This Study

Outcomes of transanal vs laparoscopic total mesorectal excision for mid and low rectal cancer under routine clinical practice conditions

Discussion

Member takes

Implication

Key Points

Cite This Study

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