What question did this study set out to answer?

The aim is to explore advances in nanotechnology for drug delivery through the skin, focusing on effective carriers.

July 10, 2026PharmaceuticalsOpen Access

Nanotechnologies for Skin Drug Delivery: Polymeric, Bio-Based, and Hybrid Nanocarriers with Clinical and Translational Perspectives

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Authors

LELina EltaibNorthern Border University HAHamoud AlotaibiNorthern Border University MHMona Al HamodNorthern Border University

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Implication

This review demonstrates improved drug delivery in dermatological applications using nanocarrier technology, suggesting significant implications for personalized treatments.

Key Points

The aim is to explore advances in nanotechnology for drug delivery through the skin, focusing on effective carriers.
Analysis of polymeric and bio-based nanocarriers for dermal and transdermal applications.
Discussion on drug transport mechanisms like intercellular and transcellular pathways.
Review of preclinical and clinical outcomes, particularly for methotrexate and vesicle formulations.
Nanocarrier-based methotrexate gels reduced PASI-like scores by over 70% in psoriatic models.
Oleic acid vesicle formulations achieved more than 95% cure rates in rodent models of tinea corporis.
Challenges in large-scale production and regulatory approval are significant in translating innovations to clinical settings.

Cite This Study

Eltaib et al. (2026) studied this question.

synapsesocial.com/papers/6a508da76eeac72a437a10ad https://doi.org/10.3390/ph19071057

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Implication

This review demonstrates improved drug delivery in dermatological applications using nanocarrier technology, suggesting significant implications for personalized treatments.

Nanotechnologies for Skin Drug Delivery: Polymeric, Bio-Based, and Hybrid Nanocarriers with Clinical and Translational Perspectives

Discussion

Member takes

Implication

Key Points

Cite This Study

Nanotechnologies for Skin Drug Delivery: Polymeric, Bio-Based, and Hybrid Nanocarriers with Clinical and Translational Perspectives

Discussion

Member takes

Implication

Key Points

Cite This Study

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