Investigates lipid signatures in traumatic brain injury, suggesting potential biomarkers for diagnosis.
Imaging mass spectroscopy reveals a unique lipid signature in positive modes. Positive MALDI-TOF images of mouse brain sections in each row display lipid signatures as indicated at a specific m/z value. The mass spectrum of individual groups of animals, Sham Vs TBI, is shown in sequence. Each image reveals the spatial distribution of distinct lipid molecular ions, utilizing a color scheme to denote the relative abundance of these specific lipids across various X-Y coordinates within the sample. The last panel to the right indicates the intensity of each m/z among the groups.
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Rasiah et al. (2026) studied this question.
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