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Captured external expert commentary on this paper, strongest first. Original sources are linked where available.
“I think physicians are still learning how to use the newer anticoagulants, and this is something that will require time.”
“The selection of an antithrombotic agent should be based on shared decision-making that takes into account risk factors, cost, tolerability, patient preference, potential for drug interactions, and other clinical characteristics, including time in INR therapeutic range if the patient has been on warfarin, irrespective of whether the atrial fibrillation pattern is paroxysmal, persistent, or permanent.”
“The long-established dogma of 'rate control for everyone' is challenged in these guidelines with catheter ablation (ie, rhythm control) being suggested as first-line therapy for selected patients.”
January et al. (2014) studied this question.
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