A working schema and diagnostic categories for platelet aggregation and secretion testing were developed and applied to 61 patients with bleeding problems.
Observational (n=61)
No
The study provides a working schema and diagnostic categories for evaluating platelet aggregation and secretion studies to help standardize clinical laboratory testing.
Platelet function testing consisting of platelet aggregation and secretion often is requested in the clinical evaluation of patients with bleeding problems. At present, there are no uniform clinical laboratory standards for the performance or interpretation of these studies. The present report describes one laboratory’s methods and interpretations of platelet aggregation and secretion studies of platelet-rich plasma using each of the common platelet agonists. Diagnostic categories for the evaluation of the platelet function testing are presented. The diagnostic categories then are applied to the evaluation of 61 patients referred to our medical center for these studies. The aims of this report are to present clinical platelet aggregation and secretion studies and to provide a working schema to evaluate these results. Our intent is to stimulate interest in the development of professional guidelines for platelet function testing in the clinical laboratory.
Zhou et al. (Tue,) conducted a observational in Bleeding problems (n=61). Platelet aggregation and secretion testing was evaluated on Diagnostic categories for the evaluation of platelet function testing. A working schema and diagnostic categories for platelet aggregation and secretion testing were developed and applied to 61 patients with bleeding problems.