What question did this study set out to answer?

The aim is to determine if routine serum magnesium testing improves prognostic assessment of 28-day mortality in emergency department admissions.

July 11, 2026Journal of the American College of Emergency Physicians OpenOpen Access

Serum Magnesium Levels as a Prognostic Marker in Emergency Department Admissions: A Landmark Retrospective Cohort Study

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Authors

KHKeita HattoriNagoya University NNNobuhiro NishiboriAichi University KFKazuhiro FuruhashiNagoya University Hospital

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Implication

Retrospective cohort study associates serum magnesium levels with 28-day mortality in emergency department patients, indicating a need for routine testing.

Key Points

The aim is to determine if routine serum magnesium testing improves prognostic assessment of 28-day mortality in emergency department admissions.
Conducted a retrospective cohort study of 43,100 adult ED admissions from January 2017 to December 2019.
Patients were stratified by magnesium levels: hypomagnesemia, normomagnesemia, hypermagnesemia.
Performed multivariable analyses adjusted for various clinical factors.
Higher mortality rates were observed in both hypomagnesemia and hypermagnesemia groups.
Hypermagnesemia retained an independent association with 28-day mortality (adjusted hazard ratio 1.73; 95% CI 1.51-2.00).
The relationship between magnesium levels and mortality was U-shaped, but risk from hypomagnesemia diminished after adjustments.

Cite This Study

Hattori et al. (2026) studied this question.

synapsesocial.com/papers/6a51dc79c18d7f28ca4ffc10 https://doi.org/10.1016/j.acepjo.2026.100463

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Implication

Retrospective cohort study associates serum magnesium levels with 28-day mortality in emergency department patients, indicating a need for routine testing.

Serum Magnesium Levels as a Prognostic Marker in Emergency Department Admissions: A Landmark Retrospective Cohort Study

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Implication

Key Points

Cite This Study

Serum Magnesium Levels as a Prognostic Marker in Emergency Department Admissions: A Landmark Retrospective Cohort Study

Discussion

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Implication

Key Points

Cite This Study

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