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This study aims to characterize the genome, antigenic properties, and pathogenicity of Fowl adenovirus isolates in Taiwan.

July 11, 2026Veterinary ResearchOpen Access

Characterization of fowl adenovirus isolates in Taiwan: genome, antigenicity, and pathogenicity

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Randomized trial investigates Fowl adenovirus characteristics in poultry, suggesting interactions with IBV influence viral dynamics.

This study aims to characterize the genome, antigenic properties, and pathogenicity of Fowl adenovirus isolates in Taiwan.
Isolated ten FAdVs from various poultry flocks between 2020 and 2025.
Conducted whole-genome sequencing to identify serotypes and assessed pathogenicity through experimental infection in chickens.
Performed co-infection experiments with infectious bronchitis virus to observe interactions.
Identified six FAdV serotypes and one isolate with intertypic recombination.
Experimental infection showed mild clinical signs and hepatic lesions, with marked hepatic involvement confirmed by histopathology.
Co-infection with IBV resulted in lower FAdV loads and prolonged viral shedding with reduced antibody responses.

Peng et al. (2026) studied this question.

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