Why the study?
Although guideline-directed vasodilator therapy and ICDs are recommended for multivessel vasospastic angina, some patients remain at risk for refractory VF, and no strategy has been established for these cases.
Does intracoronary vasodilator therapy combined with personalized drug adjustment terminate refractory ventricular fibrillation storms in patients with multivessel vasospastic angina?
Population
A 67-year-old man with refractory VF storm triggered by multivessel coronary spasm
Design
Case report
Key result
Intracoronary vasodilator therapy combined with personalised drug adjustment successfully terminated refractory ventricular fibrillation storm and prevented recurrence in a patient with multivessel spasm.
Authors
Loading...
May offer rescue option for refractory VF in multivessel spasm; leaves open need for prospective trials before practice change.
Case Report (n=1)
Does intracoronary vasodilator therapy combined with personalized drug adjustment terminate refractory ventricular fibrillation storms in patients with multivessel vasospastic angina?
Intracoronary vasodilator therapy combined with personalized drug adjustment may represent a valuable therapeutic option for refractory VF storms triggered by multivessel coronary spasm.
Ishigaki et al. (2026) conducted a case report in Refractory ventricular fibrillation storm triggered by multivessel coronary spasm (n=1). Intracoronary vasodilator administration and tailored optimisation of oral vasodilator therapy was evaluated on Termination of VF and prevention of recurrence. Intracoronary vasodilator therapy combined with personalised drug adjustment successfully terminated refractory ventricular fibrillation storm and prevented recurrence in a patient with multivessel spasm.