A Nonsporulating Sinonasal Culprit

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Key Points

To investigate the case of a patient diagnosed with sinonasal fungal infection presenting with recurrent optic neuritis.
Conducted imaging via noncontrast computed tomography of the brain and sinuses.
Performed functional endoscopic sinus surgery (FESS) to visualize nasal cavity.
Used histopathology and fungal culture to identify fungi and assess tissue involvement.
Direct examination revealed septate fungal hyphae; culture grew a white fluffy mold without sporulation.
Histopathology showed eosinophil-rich mucin with scattered fungal hyphae and no tissue invasion.
Patient improved after surgical debridement and administration of intranasal corticosteroids.

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Shows effective treatment of sinonasal fungal infections in adults, indicating potential for improved management.

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Kordcal et al. (2026) studied this question.

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