What question did this study set out to answer?

This research aims to identify baseline variables predicting 65-day all-cause mortality in adults hospitalized with invasive pneumococcal disease.

July 11, 2026HealthcareOpen Access

Baseline Predictors of Adverse Outcome and Survival in Adults Hospitalized with Invasive Pneumococcal Disease

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This research aims to identify baseline variables predicting 65-day all-cause mortality in adults hospitalized with invasive pneumococcal disease.
Conducted a retrospective cohort study of 195 adults hospitalized with invasive pneumococcal disease.
Analyzed data using logistic regression and Cox proportional hazards models, adjusting for age, sex, invasive mechanical ventilation, procalcitonin, and pH.
Primary endpoint was 65-day all-cause mortality with administrative censoring.
42 patients died during the follow-up period.
Lower admission pH was associated with increased mortality hazard (HR per 0.05-unit decrease, 1.31; 95% CI, 1.03–1.65; p = 0.026).
Higher procalcitonin levels and the need for invasive mechanical ventilation were also associated with worse outcomes.

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Implication

Retrospective cohort study evaluated factors predicting mortality in adults hospitalized with invasive pneumococcal disease, suggesting the importance of early acid-base assessment.

Cite This Study

Venturini et al. (2026) studied this question.

synapsesocial.com/papers/6a51e1f3c18d7f28ca50140c https://doi.org/10.3390/healthcare14142057

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Implication

Retrospective cohort study evaluated factors predicting mortality in adults hospitalized with invasive pneumococcal disease, suggesting the importance of early acid-base assessment.

Baseline Predictors of Adverse Outcome and Survival in Adults Hospitalized with Invasive Pneumococcal Disease

Key Points

Discussion

Implication

Cite This Study

Baseline Predictors of Adverse Outcome and Survival in Adults Hospitalized with Invasive Pneumococcal Disease

Key Points

Discussion

Implication

Cite This Study

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