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November 27, 2019SHILAP Revista de lepidopterologíaOpen Access

The SOFA score—development, utility and challenges of accurate assessment in clinical trials

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Why the study?

The use of modest serial changes in the SOFA score as a surrogate efficacy marker in sepsis trials creates a need for increased clarity on how to assess the score consistently across different circumstances.

Design

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Authors

SLSimon LambdenAlexion Pharma (Switzerland)PLPierre François LaterreUniversité Paris-SudMLMitchell M. LevyBrown University

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Implication

Guidance for consistent SOFA scoring may strengthen outcome assessment in sepsis trials; leaves open validation in prospective multicentre studies.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Lambden et al. (2019) studied this question.

synapsesocial.com/papers/69d9088cd2f7327e70ae4cc2https://doi.org/10.1186/s13054-019-2663-7
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