Key result
Giant left atrial aneurysm with extensive thrombi precipitates fatal refractory cardiogenic shock.
Why the study?
Giant left atrial aneurysm is an exceptionally rare abnormality carrying high risks of thromboembolism, compression, malignant arrhythmias, and heart failure.
Case Report (n=1)
No
Giant left atrial aneurysms can lead to catastrophic complications such as massive intracavitary thrombosis and refractory cardiogenic shock, underscoring the need for early diagnosis and intervention.
Giant left atrial aneurysms with thrombi may cause fatal shock in AF; case reports leave optimal detection and management unresolved.
A giant left atrial aneurysm is an exceptionally rare but clinically significant cardiac abnormality, most commonly associated with rheumatic mitral valve disease, long-standing atrial fibrillation, and progressive atrial remodeling related to aging. Its clinical relevance lies in the high risk of thromboembolic events, compression of adjacent structures, malignant arrhythmias, and advanced heart failure. We report the case of a 72-year-old woman with a history of persistent atrial fibrillation, chronic heart failure, chronic kidney disease, and a non-reperfused acute myocardial infarction, who presented with progressive dyspnea, precordial chest pain, and peripheral edema. Contrast-enhanced computed tomography of the chest revealed a giant aneurysmal dilation of the left atrium complicated by multiple intracavitary mural thrombi, severe cardiomegaly, and displacement of adjacent cardiac and extracardiac structures. Despite aggressive medical management, the patient rapidly deteriorated and developed refractory cardiogenic shock, culminating in cardiorespiratory arrest. This case highlights the catastrophic potential of giant left atrial aneurysms and underscores the importance of early diagnosis and timely intervention to prevent fatal complications.
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Rubio et al. (2026) conducted a case report in Giant left atrial aneurysm (n=1). Giant left atrial aneurysm was evaluated on Clinical outcome. A giant left atrial aneurysm complicated by multiple intracavitary thrombi led to refractory cardiogenic shock and fatal cardiorespiratory arrest in a 72-year-old woman.
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