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This case report aims to highlight the challenges in diagnosing myxoid fibroadenoma due to its overlapping features with other breast lesions.

July 12, 2026CureusOpen Access

Myxoid Fibroadenoma of the Breast With Radiologic-Pathologic Correlation: A Case Report

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Case report reveals a rare myxoid fibroadenoma diagnosis in a 47-year-old woman, highlighting diagnostic challenges.

This case report aims to highlight the challenges in diagnosing myxoid fibroadenoma due to its overlapping features with other breast lesions.
Imaging and core needle biopsy were used for initial evaluation of the breast mass.
Surgical excision followed the uncertainty in diagnosis from initial assessments.
Complete histopathologic examination confirmed the diagnosis of myxoid fibroadenoma.
Histopathology revealed a well-circumscribed benign biphasic fibroepithelial lesion.
The lesion contained abundant hypocellular myxoid stroma without cytologic atypia or increased mitotic activity.
Awareness of myxoid fibroadenoma is crucial to prevent misdiagnosis with other breast neoplasms.

Milonaki et al. (2026) studied this question.

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