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July 12, 2026Scientific DataOpen Access

A curated reference database of membrane-permeability annotations for biological dyes

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Authors

BWBo WangBLBo LiZYZiLong Yuan

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Overview

Curated dataset provides membrane permeability data for biological dyes, supporting efficient experimental applications.

Key Points

  • The goal is to create a comprehensive database of membrane permeability information for biological dyes.
  • Developed DyePermDB with 251 dyes and standard chemical identifiers
  • Implemented a two-level annotation framework for permeability status and contexts
  • Performed quality-control and standardisation using an RDKit-based workflow
  • DyePermDB includes structured annotations such as chemical form and evidence context
  • Technical validation through exploratory FP4 fingerprint analyses confirmed internal classification
  • Provides reusable resources for dye annotation review and computational studies

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/6a532fb44f7abc118aded1eehttps://doi.org/10.1038/s41597-026-07849-1
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