Key result
Negative somatostatin receptor scintigraphy helps exclude cardiac sarcoidosis in a patient with complete AV block.
Why the study?
Inadequate fasting during FDG PET/CT can cause physiological myocardial uptake, complicating the diagnosis of cardiac sarcoidosis in complete atrioventricular block.
Case Report (n=1)
No
Somatostatin receptor scintigraphy (SRS) may be a useful adjunctive imaging modality to exclude cardiac sarcoidosis in patients with malignancies and cardiovascular diseases, as it does not require fasting and avoids the physiological myocardial uptake often seen on FDG PET/CT.
May support SRS to exclude cardiac sarcoidosis when FDG uptake is ambiguous post-tumor surgery; hypothesis-generating and leaves open prospective validation.
Cardiac sarcoidosis is a major cause of complete atrioventricular block. Although fluorodeoxyglucose-positron emission tomography (FDG PET/CT) is valuable for the diagnosis, inadequate fasting may result in a physiological myocardial uptake, making interpretation difficult. Somatostatin receptor scintigraphy (SRS), which does not require fasting, has been reported to detect myocardial inflammation in patients with DCM. We herein report the case of a 72-year-old man who developed complete atrioventricular block after surgery for a duodenal neuroendocrine tumor. In this patient, FDG PET/CT showed a marked cardiac uptake, while SRS findings suggested a low likelihood of cardiac sarcoidosis. In patients with malignancies and cardiovascular diseases, SRS may be useful for excluding cardiac sarcoidosis.
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Kurokawa et al. (2026) conducted a case report in Complete atrioventricular block and suspected cardiac sarcoidosis (n=1). Somatostatin receptor scintigraphy (SRS) vs. FDG PET/CT was evaluated. Somatostatin receptor scintigraphy demonstrated no myocardial uptake, aiding in the exclusion of cardiac sarcoidosis in a patient with a duodenal neuroendocrine tumor and complete atrioventricular block.
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