What question did this study set out to answer?

This report aims to examine the pathophysiology, clinical presentation, diagnosis, and management of AA amyloidosis secondary to renal cell carcinoma.

July 13, 2026CureusOpen Access

Amyloidosis in the Context of Renal Cell Carcinoma: A Case Report and Literature Review

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Authors

SMSaja MahmoodSultan Qaboos University Hospital AAAya AalHamad KZKhalfan Al Zeedy

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Implication

Case report details the diagnosis and challenges of treating amyloidosis in an elderly patient with renal cell carcinoma, indicating clinical implications.

Key Points

This report aims to examine the pathophysiology, clinical presentation, diagnosis, and management of AA amyloidosis secondary to renal cell carcinoma.
A case study of an 86-year-old male with recurrent vomiting, proteinuric acute kidney injury, and nephrotic syndrome.
Diagnosis confirmed through kidney biopsy identifying grade 3 renal cell carcinoma and systemic AA amyloidosis.
Literature review highlights the rarity and diagnostic challenges of this association.
AA amyloidosis associated with renal cell carcinoma resulted in progressive renal function deterioration despite comprehensive management.
Patient transitioned to palliative care due to the high surgical risk and inoperable tumor.
Community-acquired pneumonia complicated the patient's admission and treatment process.

Cite This Study

Mahmood et al. (2026) studied this question.

synapsesocial.com/papers/6a54807d475c38bf615a5453 https://doi.org/10.7759/cureus.112409

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Implication

Case report details the diagnosis and challenges of treating amyloidosis in an elderly patient with renal cell carcinoma, indicating clinical implications.

Amyloidosis in the Context of Renal Cell Carcinoma: A Case Report and Literature Review

Discussion

Member takes

Implication

Key Points

Cite This Study

Amyloidosis in the Context of Renal Cell Carcinoma: A Case Report and Literature Review

Discussion

Member takes

Implication

Key Points

Cite This Study

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