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July 13, 2026The Lancet1,530 citations

Acute myocardial infarction

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GRGrant W. ReedJRJeffrey RossiCCChristopher P. Cannon

Key Result

This seminar reviews the pathophysiology, epidemiological trends, and modern management of acute myocardial infarction, highlighting recent advances in reperfusion and pharmacological treatments.

Key Points

  • The aim is to review current management strategies and recent advancements in the treatment of acute myocardial infarction.
  • Analyses of epidemiological trends and pathophysiology of acute myocardial infarction.
  • Discussion of invasive strategies and immediate revascularisation methods.
  • Review of pharmacological treatments, including antiplatelet and anticoagulant therapies.
  • Recent advancements in reperfusion strategies significantly improve patient outcomes.
  • Increased use of secondary prevention strategies, such as statins, reduces morbidity rates.
  • Improvements in risk stratification enhance early detection and management efficiency.

PICO

P
Population
Acute myocardial infarction
I
Intervention / Comparator
Modern management of acute myocardial infarction

Abstract

Acute myocardial infarction has traditionally been divided into ST elevation or non-ST elevation myocardial infarction; however, therapies are similar between the two, and the overall management of acute myocardial infarction can be reviewed for simplicity. Acute myocardial infarction remains a leading cause of morbidity and mortality worldwide, despite substantial improvements in prognosis over the past decade. The progress is a result of several major trends, including improvements in risk stratification, more widespread use of an invasive strategy, implementation of care delivery systems prioritising immediate revascularisation through percutaneous coronary intervention (or fibrinolysis), advances in antiplatelet agents and anticoagulants, and greater use of secondary prevention strategies such as statins. This seminar discusses the important topics of the pathophysiology, epidemiological trends, and modern management of acute myocardial infarction, focusing on the recent advances in reperfusion strategies and pharmacological treatment approaches.

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Cite This Study

Reed et al. (2016) conducted a review in Acute myocardial infarction. Modern management of acute myocardial infarction was evaluated. This seminar reviews the pathophysiology, epidemiological trends, and modern management of acute myocardial infarction, highlighting recent advances in reperfusion and pharmacological treatments.

synapsesocial.com/papers/6a555655615b3ba82daf91bchttps://doi.org/10.1016/s0140-6736(16)30677-8
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