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June 10, 2010New England Journal of MedicineOpen Access

Population Trends in the Incidence and Outcomes of Acute Myocardial Infarction

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Population

Large community-based population

Design

Cohort

Authors

Robert W. YehRobert W. YehInterventional / Structural CardiologySSStephen SidneyPreventive CardiologyMCMalini ChandraKaiser Permanente

Discussion

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Implication

Supports prevention efforts; extends observational trends but leaves causal drivers and long-term effects open.

Key Points

  • To evaluate temporal trends in the incidence and short-term fatality rates of acute myocardial infarction subtypes within a community setting.
  • Assessed population trends in acute myocardial infarction incidence and short-term case fatality rates within a large community-based cohort.
  • Stratified longitudinal data by ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI).
  • Overall myocardial infarction incidence decreased significantly after 2000, and STEMI incidence decreased markedly after 1999.
  • Short-term case fatality rates declined, driven in part by lower STEMI incidence and decreased post-NSTEMI mortality.

Structured PICO

P
Population
Large community-based population
O
Outcome
Incidence of myocardial infarction (including ST-segment elevation myocardial infarction) and short-term case fatality rateshard clinical

Population-level incidence and short-term case fatality rates of acute myocardial infarction have significantly decreased since 2000, largely driven by a reduction in STEMI incidence.

Cite This Study

Yeh et al. (2010) studied this question.

synapsesocial.com/papers/69d5741ddef4cefba5c22a34https://doi.org/10.1056/nejmoa0908610

Topics

Statin therapy
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