Key result
Physical inactivity is linked to ~2.6-fold higher odds of failing to achieve LDL-C goals.
Why the study?
Social determinants of health significantly influence cardiovascular outcomes, but their role in achieving lipid profile goals in older adults remains underexplored.
Are social determinants of health associated with the nonachievement of LDL-C and non-HDL-C goals in older adults?
Cross-Sectional (n=1,270)
Yes
Are social determinants of health associated with the nonachievement of LDL-C and non-HDL-C goals in older adults?
Social determinants of health, such as female sex, lack of health system coverage, and physical inactivity, are significantly associated with poor lipid control and failure to meet cholesterol targets in older Colombian adults.
Answers are grounded in this paper and cite their sources.
May warrant inactivity screening in older adults missing LDL-C targets; leaves open whether activity interventions improve goal attainment.
BACKGROUND: Social determinants of health (SDH) significantly influence cardiovascular outcomes; however, their role in achieving lipid profile goals in older adults remains underexplored. This study aimed to evaluate the association between SDH and nonachievement of LDL cholesterol (LDL-C) and non-HDL cholesterol (non-HDL-C) targets in Colombian adults aged ≥ 60 years. METHODS: A cross-sectional analysis was conducted using data from 1270 participants in the SABE Colombia 2015 study. Logistic regression was applied to estimate odds ratios (ORs) for not achieving LDL-C and non-HDL-C goals on the basis of the Framingham, ASCVD 2013, and SCORE2 models. RESULTS: Non achieving LDL-C goals were associated with female sex, lack of affiliation with the health system and physical inactivity. Physical inactivity was associated with noncompliance on non-HDL-C goals, among others. CONCLUSIONS: SDH are strongly associated with poor lipid control. Addressing modifiable SDHs could enhance cardiovascular risk management in older adults.
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Bueno et al. (2025) conducted a cross-sectional in Older adults (primary prevention for cardiovascular disease) (n=1,270). Social determinants of health (e.g., physical inactivity, female sex, lack of health system affiliation) vs. Absence of these risk factors (e.g., physically active, male sex, affiliated with health system) was evaluated on Nonattainment of LDL-C goal according to Global SCORE2 risk categories (for physical inactivity) (OR 2.60, 95% CI 1.45-4.67). Physical inactivity was significantly associated with an increased odds of not achieving LDL-C goals based on the Global SCORE2 model (OR 2.60, 95% CI 1.45-4.67) among older Colombian adults.
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