Key result
A 16-week high-intensity interval training program improved VO2max by 5.92 mL/kg/min and reduced systolic blood pressure by 8.70 mmHg in hypertensive patients with excessive adiposity, independent of changes in substrate utilization.
Why the study?
Regular exercise training lowers resting blood pressure, but little is known about substrate metabolism in this setting.
Does 16-weeks of HIIT improve cardiorespiratory fitness, blood pressure, and substrate utilization in physically inactive overweight/obese patients with varying baseline blood pressure?
Comparison
HIIT in hypertensive vs pre-hypertensive vs normotensive control participants
Design
Intervention study
Follow-up
16 weeks
Authors
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May support HIIT for fitness and BP gains in hypertensive patients with adiposity; leaves open mechanisms and need for larger trials.
Does 16-weeks of HIIT improve cardiorespiratory fitness, blood pressure, and substrate utilization in physically inactive overweight/obese patients with varying baseline blood pressure?
Mean Difference: 5.92 (95% CI 4.16–7.68)
Absolute Event Rate: 5.92% vs 3.34%
p-value: p=0.083
A 16-week HIIT intervention improves cardiorespiratory fitness and blood pressure in overweight/obese individuals regardless of baseline blood pressure, independent of substrate utilization changes.
Delgado‐Floody et al. (2020) studied Prehypertension and hypertension with excessive adiposity (n=42). High-Intensity Interval Training (HIIT) vs. Normotensive control group (H-CG) receiving the same HIIT was evaluated on Change in maximal oxygen uptake (VO2max) from baseline (MD 5.92, 95% CI 4.16 to 7.68, p=0.083). A 16-week high-intensity interval training program improved VO2max by 5.92 mL/kg/min and reduced systolic blood pressure by 8.70 mmHg in hypertensive patients with excessive adiposity, independent of changes in substrate utilization.
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