June 1, 2003Lupus
Proposal for a new definition of congenital complete atrioventricular block
Key result
A systematic review of 1,825 cases found complete AV blocks detected in utero differ from those detected later in life, prompting a new definition of congenital complete AV block.
Study Design
Type
Systematic Review (n=1,825)
Structured PICO
P
Population
1,825 cases of congenital complete atrioventricular block from 38 separate studies systematically reviewed to propose a new definition.
Proposes a modern, standardized definition of congenital complete AV block as being diagnosed in utero, at birth, or within the neonatal period (0-27 days after birth).
Authors
Discussion
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Implication
May guide neonatal risk stratification and counseling; extends classifications by distinguishing in utero from later-onset AV block.
Cite This Study
Brucato et al. (2003) conducted a systematic review in Congenital complete atrioventricular block (n=1,825). Complete AV blocks detected in utero vs. Blocks detected later in life was evaluated on Differences in pathogenesis, prognosis, and recurrence risk. A systematic review of 1,825 cases found complete AV blocks detected in utero differ from those detected later in life, prompting a new definition of congenital complete AV block.