Key result
Reoperative mitral valve replacement demonstrated an in-hospital mortality rate of 5.41%, with mortality significantly associated with higher EuroSCORE and infectious complications.
Why the study?
Increasing rates of mitral valve replacement and longer life expectancy have led to more redo procedures, which remain a clinical challenge.
Observational (n=37)
No
Reoperative mitral valve replacement demonstrates an acceptable in-hospital mortality of 5.41% and a 5-year survival rate of 72%, with mortality primarily associated with baseline EuroSCORE and infectious complications.
Supports EuroSCORE for risk stratification in reoperative mitral replacement; leaves open need for prospective validation of modifiable factors.
Overview: Mitral valve (MV) disease is the most common valvular disease; surgery is the definitive treatment when it is no longer possible for conservative treatment. The number of patients undergoing MV replacement surgery is increasing and life expectancy is increasing, leading to an inevitable increase in the number of patients having to undergo reoperative MV replacement. Redo MV replacement remains a challenge. The study aimed to evaluate the results of redo-mitral valve replacement surgery. Method: This is a retrospective, descriptive study of patients who underwent reoperative mitral valve replacement at cardiovascular center – E hospital, from January 2015 to December 2019. Results: Thirty seven patients (24 females) underwent redo-MVR with either bioprosthetic (n = 18) or mechanical valves (n = 18). Median age of patients was 53 years (range 30–78 years), and the mean additive EuroSCORE was 8.15%. Median time to re-operation was 5.37± 2.78 years for first time redo-MVR and 3 years for second-time redo-MVR. Indications included prosthetic endocarditis (n = 9), para-prosthetic leak (n = 1), structural valve degeneration (n = 12), prosthetic valve thrombosis (n = 15). In-hospital mortality was 5.41%. Mean hospital stay was 27.54± 15.93 days. Actuarial survival at 1 and 5 years was 81 ± 5% and 72 ± 6%, respectively. Multivariate analysis showed that mortality was associated with Euroscore and infectious complications. Conclusion: Mitral valve replacement surgery is safe and effective in improving clinical symptoms and laboratory parameters. Regular postoperative monitoring is required to reduce the risk of reoperation due to prosthetic valve thrombosis. Good infection prevention and management could reduce mortality and length of hospital stay.
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Nghia et al. (2022) conducted an observational in Mitral valve disease requiring reoperation (n=37). Reoperative mitral valve replacement was evaluated on In-hospital mortality. Reoperative mitral valve replacement demonstrated an in-hospital mortality rate of 5.41%, with mortality significantly associated with higher EuroSCORE and infectious complications.
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