Medical Toxicology Screening Protocols in Dental Pharmacovigilance Review

Dental pharmacovigilance centers on the drugs dentists prescribe—local anesthetics, antibiotics, analgesics, sedatives—and their safety across patient populations. This note examines screening protocols that dental clinics and practices can implement to detect adverse events and drug-related harms. We review toxicological principles applied to pharmacy screening, patient communication about side effects, and escalation pathways when adverse events occur. Specific protocols address allergy verification, drug-drug interaction checking, renal and hepatic dose adjustment, and recognition of rare but serious toxicities (e.g., anaphylaxis to amoxicillin, hepatotoxicity from dental antibiotics in compromised patients). The framework translates toxicology into systematic dental practice.