Subcutaneous implantable cardioverter-defibrillator implantation induced a silicone allergy presenting as a granulomatous lesion 7 months post-procedure, necessitating complete system removal.
Case Report (n=1)
Silicone-related hypersensitivity should be considered in cases of noninfectious wound complications following S-ICD implantation.
ABSTRACT Background Allergic reactions associated with subcutaneous implantable cardioverter‐defibrillator (S‐ICD) are extremely rare, and silicone‐related cases are scarcely reported. Methods and Results A 54‐year‐old man with a transvenous implantable cardioverter‐defibrillator (TV‐ICD) for idiopathic ventricular fibrillation underwent removal of an infected TV‐ICD system, followed by S‐ICD implantation. Seven months later, a granulomatous lesion developed at the xiphoid incision site without signs of infection. Conservative management was initially selected; however, progressive wound deterioration and eventual device exposure necessitated complete system removal. Patch testing demonstrated a positive reaction to silicone, a device component corresponding to the lesion site. Conclusions This case highlights that silicone‐related hypersensitivity, although extremely rare, should be considered when evaluating noninfectious wound complications after S‐ICD implantation.
Shinkai et al. (Sun,) conducted a case report in Silicone allergy associated with subcutaneous implantable cardioverter-defibrillator (n=1). Subcutaneous implantable cardioverter-defibrillator (S-ICD) was evaluated on Development of a granulomatous lesion and silicone allergy. Subcutaneous implantable cardioverter-defibrillator implantation induced a silicone allergy presenting as a granulomatous lesion 7 months post-procedure, necessitating complete system removal.