Key result
Endovascular repair of abdominal aortic aneurysm reduced 30-day operative mortality compared to open repair (1.8% vs 4.3%; OR 0.39, 95% CI 0.18-0.87, P=0.02), with no difference in long-term mortality.
Why the study?
Does endovascular repair improve long-term mortality compared to open surgical repair in patients with large abdominal aortic aneurysms?
RCT (n=1,252)
Yes
Does endovascular repair improve long-term mortality compared to open surgical repair in patients with large abdominal aortic aneurysms?
Odds Ratio: 0.39 (95% CI 0.18–0.87)
Absolute Event Rate: 1.8% vs 4.3%
p-value: p=0.02
Endovascular repair of large abdominal aortic aneurysms provides an early survival benefit over open repair, but this advantage is lost long-term due to late complications and reinterventions.
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Favors endovascular repair to reduce early mortality in suitable patients; confirms no long-term survival advantage despite higher reinterventions.
Nora Toma (2010) conducted an RCT in Abdominal aortic aneurysm (n=1,252). Endovascular repair vs. Open repair was evaluated on 30-day operative mortality (OR 0.39, 95% CI 0.18 to 0.87, p=0.02). Endovascular repair of abdominal aortic aneurysm reduced 30-day operative mortality compared to open repair (1.8% vs 4.3%; OR 0.39, 95% CI 0.18-0.87, P=0.02), with no difference in long-term mortality.
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