Key result
Among diabetic patients attending a rural clinic in Malawi, the prevalence of chronic kidney disease was 8.8%, and was significantly associated with older age, higher systolic blood pressure, and lower fasting blood sugar.
Why the study?
Patients with diabetes are at high risk of renal insufficiency and CKD, making CKD screening essential as part of their care.
Cross-Sectional (n=148)
Yes
There is a moderately high prevalence of renal insufficiency and CKD among diabetic patients in rural Malawi, highlighting the need for routine screening.
Answers are grounded in this paper and cite their sources.
Supports CKD screening in diabetic care in Malawi; hypothesis-generating for prevalence estimates in similar settings.
Patients with diabetes are at high risk of developing renal insufficiency and chronic kidney disease (CKD). As a result, screening for CKD is essential in diabetic patients as part of their care. This study investigated the prevalence of renal insufficiency, CKD, and correlates of CKD in diabetic patients attending Integrated Chronic Care Clinics in Neno District, Malawi. Of 203 diabetic patients, 148 (73%) were screened for CKD by measurement of serum creatinine and urinary protein between April 2016 and January 2019. 39.2% (n = 58) of the patients had abnormal estimated glomerular filtration rate (eGFR), as estimated by CKD Epidemiology Collaboration formula and/or ≥ 2+ urine protein. 13.5% (95% CI 8.4–20.0%, 20/148) of the patients had renal insufficiency based on eGFR of less than 60 ml/min/1.73 m2. 8.8% (95% CI 4.8–14.6%, 13/148) had CKD based on eGFR of less than 60 ml/min/1.73 m2 measured twice at least 3 months apart. In bivariate analysis, CKD was associated with older age, high systolic blood pressure and lower fasting blood sugar. Despite the low sample size, the study showed a moderately high prevalence of renal insufficiency and CKD in a rural cohort of diabetic patients in Malawi.
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Kachimanga et al. (2019) conducted a cross-sectional in Diabetes mellitus (n=148). Diabetes mellitus was evaluated on Prevalence of chronic kidney disease (CKD) (95% CI 4.8-14.6). Among diabetic patients attending a rural clinic in Malawi, the prevalence of chronic kidney disease was 8.8%, and was significantly associated with older age, higher systolic blood pressure, and lower fasting blood sugar.
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