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July 15, 2026BMC OphthalmologyOpen Access

Anterior segment optical coherence tomography enables repeat Descemet Membrane Endothelial Keratoplasty instead of penetrating keratoplasty in a patient with a prominent corneal opacity following DMEK failure: a case report

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Authors

VEVerena A. EnglmaierSBStefanie BobeNRN. Rolf

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Overview

Randomized trial demonstrates improved visual acuity in a patient with corneal opacity, suggesting less invasive approaches.

Key Points

  • To evaluate the effectiveness of using anterior segment optical coherence tomography in guiding surgical decisions for corneal transplant procedures after DMEK failure.
  • A 48-year-old female underwent planned penetrating keratoplasty (PKP) after DMEK failure.
  • Preoperative imaging using anterior segment optical coherence tomography (AS-OCT) was performed to assess corneal structure.
  • Surgical intervention involved anterior lamellar keratectomy combined with repeat DMEK.
  • Best-corrected visual acuity improved from counting fingers to 20/40 (0.5) six weeks postoperatively.
  • AS-OCT pachymetry measurement decreased from 1200 µm to 470 µm following the procedure.

Cite This Study

Englmaier et al. (2026) studied this question.

synapsesocial.com/papers/6a5722be88b21df87547fa89https://doi.org/10.1186/s12886-026-05070-7
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